Tianjin Tianyao Pharmaceuticals Co., Ltd

EP/USP

20180706-209-J-239

(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione

1-dehydro-6α-methylhydrocortisone

6α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione

delta(1)-6alpha-Methylhydrocortisone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone.9 It was first described in the literature in the late 1950s.

Methylprednisolone was granted FDA approval on 24 October 1957.

83-43-2

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Wuhan Wuyao Pharmaceutical Co., Ltd

EP

20160114-104-F-83-03(6)

2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol

1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole

1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole

1-(β-ethylol)-2-methyl-5-nitro-3-azapyrrole

1-(β-hydroxyethyl)-2-methyl-5-nitroimidazole

1-(β-oxyethyl)-2-methyl-5-nitroimidazole

2-methyl-1-(2-hydroxyethyl)-5-nitroimidazole

2-methyl-3-(2-hydroxyethyl)-4-nitroimidazole

2-methyl-5-nitroimidazole-1-ethanol

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a wide variety of infections. It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections.

443-48-1

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Symbiotica Speciality Ingredients Sdn. Bhd.

EP

20210225-211-J-570

9,21-Dichloro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-diene-17-yl furan-2-carboxylate

Sch-32088

Elocon

Nasonex

Mometasone furoate is a topical corticosteroids of moderate efficacy.

The mechanism of action of topical corticosteroids is not well defined. However, it is thought that the three important actions: anti-inflammatory action, immunosuppressive action, and proliferation inhibitory action, are combined to show the effect.

83919-23-7

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Chongqing Huapont Shengchem Pharmaceutical Co., Ltd.

USP

20200618-211-J-455

1-naphthalenemethanamine,N-methyl-N-(3-phenyl-2-propenyl)-,hydrochloride(E)-(E)-N-Cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride

It is a synthetic alkylamine derivative with a broad antifungal range.

It inhibits squalene epoxidases, which are important enzymes for sterol biosynthesis, and exhibits antifungal action by depleting ergosterol in the fungal cell membrane.

65473-14-5

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Divi’s Laboratories Limited.

USP

20130821-143-I-336-08(3)

(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid

(+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid

(+)-(S)-Naproxen

(+)-2-(6-Methoxy-2-naphthyl)propionic acid

(+)-2-(Methoxy-2-naphthyl)-propionic acid

(+)-2-(Methoxy-2-naphthyl)-propionsäure

(+)-Naproxen

(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid

(S)-(+)-Naproxen

(S)-2-(6-Methoxy-2-naphthyl)propanoic acid

(S)-2-(6-Methoxy-2-naphthyl)propionic acid

(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid

(S)-Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given it's overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. Naproxen is available in both immediate and delayed release formulations, in combination with sumatriptan to treat migraines, and in combination with esomeprazole to lower the risk of developing gastric ulcers.

22204-53-1

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Zhejiang Charioteer Pharmaceutical Co., Ltd.

USP

20130121-143-I-209-04(6)

N/A

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given it's overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. Naproxen is available in both immediate and delayed release formulations, in combination with sumatriptan to treat migraines, and in combination with esomeprazole to lower the risk of developing gastric ulcers

26159-34-2

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Zhejiang East- Asia Pharmaceutical Co., LTd

USP

20070723-89-E-2-02(20)

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

82419-36-1

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Mylan Laboratories Limited

EP

20191217-209-J-318

(−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine

(3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. Because of its potent inhibition of serotonin reuptake, paroxetine is more likely to cause withdrawal effects upon cessation. Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class. The controlled release formulation was designed to decrease the likelihood of nausea that is sometimes associated with paroxetine.

61869-08-7

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Chongqing Shenghuaxi Pharmaceutical Co., Ltd.

JP

20180809-171-I-571-08

N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenylbutoxy)benzamide

Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

150821-03-7

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Symbiotica Speciality Ingredients Sdn. Bhd.

EP

20210302-71-B-441-11

11β,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate

Ak-tate

Hostacortin H

Inflanefran

Pred Forte

Pred Mild

Sterane

Prednisolone acetate inhibits the migration of polymorphonuclear luekocytes and reduces the inflammatory response by reducing the increased capillary permeability.

It suppresses the immune response by reducing the activity and volume of the lymphatic system.

52-21-1

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NEWCHEM S.p.A
[프레드니솔론 제조소①] Hanan Lihua Pharmaceutical Co., Ltd.
[프레드니솔론 제조소②] Tianjin Tianyao Pharmaceuticals co., Ltd
[프레드니솔론 제조소③] Zhejiang Xianju Pharmaceutical Co., Ltd.

In-house

2011209-71-B-322-06(6)

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-5,17-dione

1,2-Dehydrocortisone

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.

Prednisone was granted FDA approval on 21 February 1955.

53-03-2

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Mylan Laboratories Limited

Qilu Tianhe Pharmaceutical Co., Ltd.

USP

20120713-172-I-90-05

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as Clozapine and Olanzapine.

111974-72-2

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Mylan Laboratories Limited

In-house

수289-6-ND

(1R)-N-propargylindan-1-amine

(R)-indan-1-yl-prop-2-ynyl-amine

(R)-N-2-Propynyl-1-indanamine

Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

136236-51-6

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Suzhou Tianma Specialty Chemicals Co.,Ltd
Jiangxi Synergy Pharmaceutical Co., Ltd

JP

20160725-4-B-387-21(2)
20070504-4-B-240-14(3)

90098-04-7

N/A

Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.

90098-04-7

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Mylan Laboratories Limited
Aurobindo Pharma ltd.

EP

20151130-10-C-349-20
20070521-10-C-231-14(1)

RAPZEAPATHNIPO-UHFFFAOYSA-N

N/A

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia, bipolar mania, and as an adjunct in severe depression for example. It is one of the most widely used SGAs.

Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical pathways, respectively. Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.

Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors

106266-06-2

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