EGF stands for epidermal growth factor, which is a single-chain, non-glycosylated protein that naturally occurs in our skin cells. Its main purpose is to heal our skin by promoting DNA synthesis and cell proliferation. Once it binds to EGFR, which is its receptor, on the surface of the cell, the combination of the two kickstarts several signaling pathways that ultimately lead to results such as cell proliferation, differentiation, and survival.
EGF has many benefits for your skin, including wrinkle improvement, hydration, and pigmentation prevention. The process by which EGF encourages cell growth also stimulates the division of keratinocytes and fibroblasts, which then synthesize fibrous proteins that improve skin elasticity such as collagen and elastin.
Because EGF repairs skin by stimulating the growth of new skin cells, it also enhances skin barrier. This allows skin to hold on to moisture better, so your skin becomes smoother and softer. Lastly, it inhibits melanin production during the wound healing process, so it improves acne marks and other forms of hyperpigmentation