Biomaterials specialized company

ACE BIOPHARM

We have the solution you need

Excipients (Pharmaceutical Notification)

According to Pharmacopoeia General Principles, additives is defined as "A material other than the active ingredient contained in the Formulation. It is used for the purpose of enhancing usefulness, facilitating formulation, stabilizing formulation, and improving the appearance of medicines.

 

Additive products include excipient, stabilizers, preservatives, buffers, acidifier, suspending agent, emulsifiers, aromatic agents, solvents, colourants, and thickner.

 

However, the additives are safe and not directly pharmacological in the dosage of the drug, and do not change the therapeutic effects of the drug or interfere with the testing."

 

Its purpose is 1) to enhance stability, bioavailability and etc., 2) to preserve or maintain the quality of the drug during use and storage, and 3) to enhance the drug economy by controlling the physical characteristics.

  • [Excipients(Thinner)]Carboxymethylcellulose sodium

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

    N/A

     

    Pharmaceutical Notification number

    11

     

    IUPAC Name

    N/A

     

    Synonyms

    N/A

     

    Description

    Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining. The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time in the ocular surface. Sodium carboxymethylcellulose is the most commonly used salt.

     

    CAS No.

    9000-11-7

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Croscarmellose sodium

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

    N/A

     

    Pharmaceutical Notification number

    10

     

    IUPAC Name

    acetic acid;2,3,4,5,6-pentahydroxyhexanal

     

    Synonyms

    N/A

     

    Description

    Sodium croscarmellose is an internally cross-linked sodium carboxymethylcellulose for use as a superdisintegrant in pharmaceutical formulations

     

    CAS No.

    9000-11-7

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Glycerin

    Manufacturer

    FPG Oleochemicals

     

    Specification

    USP

     

    Pharmaceutical Notification number

    1

     

    IUPAC Name

    propane-1,2,3-triol

     

    Synonyms

    1,2,3-propanetriol

    1,2,3-trihydroxypropane

    Glycerin, anhydrous

    Propanetriol

    Trihydroxypropane

     

    Description

    Glycerol (/ˈɡlɪsərɒl/; also called glycerine or glycerin) is a simple polyol compound. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in those lipids known as glycerides. Due to having antimicrobial and antiviral properties it is widely used in FDA approved wound and burn treatments. It can also be used as an effective marker to measure liver disease. It is also widely used as a sweetener in the food industry and as a humectant in pharmaceutical formulations. Owing to the presence of three hydroxyl groups, glycerol is miscible with water and is hygroscopic in nature.

     

    CAS No.

    56-81-5

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Hypromellose 2208

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

    USP

     

    Pharmaceutical Notification number

    3

     

    IUPAC Name

    N/A

     

    Synonyms

    Cellulose hydroxypropyl methyl ether

    Cellulose, 2-hydroxypropyl methyl ether

    Hydroxypropyl methylcellulose 2208

    Hydroxypropyl methylcellulose 2910

    Hydroxypropyl methylcellulose 4000

    Hydroxypropyl methylcelluloses

    Hydroxypropylmethylcellulose

     

    Description

    Hypromellose, or hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations. It is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong its therapeutic effects. Hypromellose is also found in eye drops as a lubricant.

     

    CAS No.

    9004-65-3

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Hypromellose 2910

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

    USP

     

    Pharmaceutical Notification number

    4

     

    IUPAC Name

    N/A

     

    Synonyms

    Cellulose hydroxypropyl methyl ether

    Cellulose, 2-hydroxypropyl methyl ether

    Hydroxypropyl methylcellulose 2208

    Hydroxypropyl methylcellulose 2910

    Hydroxypropyl methylcellulose 4000

    Hydroxypropyl methylcelluloses

    Hydroxypropylmethylcellulose

     

    Description

    Hypromellose, or hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations. It is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong its therapeutic effects. Hypromellose is also found in eye drops as a lubricant.

     

    CAS No.

    9004-65-3

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Hypromellose phthalate

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

    USP

     

    Pharmaceutical Notification number

    6

     

    IUPAC Name

    N/A

     

    Synonyms

    HydroxyPropyl MethylCellulose Phthalate

    Cellulose, 2-Hydroxypropyl methylether, phthalic acid ester

    HPMCP

     

    Description

    Hypromellose phthalate (hydroxypropyl methylcellulose phthalate, or HPMCP) is a phthalic acid ester of hydroxypropyl methylcellulose. In the pharmaceutical industry, hypromellose phthalate is used as a coating agent for tablets and granules. It is a colorless, odorless white powder.

     

    Hypromellose phthalate was introduced in 1971 as a cellulose derivative for enteric coating. An enteric coating agent is used to protect drugs from degradation by gastric acid or to present them from causing side effects in the stomach. It is widely used as an enteric coating agent by the pharmaceutical industry. HPMCP has been admitted into the U.S. National Formulary (US/NF). HPMCP is also used in sustained-release preparations, in binders and as microcapsule bases.

     

    CAS No.

    9050-31-1

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Low-Substituted Hydroxypropyl Cellulose

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

     

     

    Pharmaceutical Notification number

    9

     

    IUPAC Name

    N/A

     

    Synonyms

    N/A

     

    Description

    Hydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis, and as a lubricant for artificial eyes. As a food additive, hydroxypropyl cellulose is used as a thickener and as an emulsion stabilizer.

     

    CAS No.

    9004-64-2

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Propylene Glycol

    Manufacturer

    Dow Chemical Thailand Ltd.

     

    Specification

     

     

    Pharmaceutical Notification number

    7

     

    IUPAC Name

    propane-1,2-diol

     

    Synonyms

    N/A

     

    Description

    A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.

     

    CAS No.

    57-55-6

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Sodium stearyl fumarate

    Manufacturer

    Anhui sunhere pharmaceutical excipients

     

    Specification

    USP

     

    Pharmaceutical Notification number

    5

     

    IUPAC Name

    sodium;(E)-4-octadecoxy-4-oxobut-2-enoate

     

    Synonyms

    Pruv

    SODIUM OCTADECYL FUMARATE

    UNII-7CV7WJK4UI

     

    Description

    Sodium Stearyl Fumarate (SSF) is used as a lubricant in tableting to reduce the friction between the tablet and the die wall and to prevent adhesion of the material to punches or the die wall in the pharmaceutical industries. It is used also as a lubricant in the manufacturing of capsules and other oral dosage forms. Sodium stearyl fumarate is also used in food production as a dough conditioner, a conditioning agent, and a stabilizing agent.

     

    CAS No.

    4070-80-8

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Sorbitol Sol.70% (Crystalline)

    Manufacturer

    Ksyap Sweetners Limited

     

    Specification

     

     

    Pharmaceutical Notification number

    8

     

    IUPAC Name

    (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol

     

    Synonyms

    N/A

     

    Description

    A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.

     

    CAS No.

    50-70-4

     

    Certificate of Analysis

    If you need more information, please contact us.

     

  • [Excipients(Thinner)]Sorbitol Sol.70% (Non Crystalline)

    Manufacturer

    Ksyap Sweetners Limited

     

    Specification

    EP

     

    Pharmaceutical Notification number

    2

     

    IUPAC Name

    (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol

     

    Synonyms

    (−)-sorbitol

    D-(−)-sorbitol

    D-glucitol

    D-Sorbitol

    G-ol

    L-Gulitol

     

    Description

    A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.

     

    CAS No.

    50-70-4

     

    Certificate of Analysis

    If you need more information, please contact us.

     

[06784] 41, Dongsan-ro 8-gil, Seocho-gu, Seoul, Republic of Korea
CEO : Min-Byoung Gyu /  TEL : +82-2-579-1056  /  FAX : +82-2-6008-3356  /  E-mail : ace@acebiopharm.com

Copyright © 2010 ABP company. All Rights Reserved.